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A 70-year-old male presents to your clinic with the chief complaint of leg discomfort. He states that he has difficulty sleeping at night due to these symptoms. Movement of his limbs gives transient relief. Serum ferritin levels were within normal limits. Which of the following therapeutic options is the most appropriate treatment for his disorder?
A 36-year-old female with bilateral lower extremity weakness, hyperreflexia, and difficulty emptying her bladder gets an urgent MRI with contrast of her thoracic spine (T2 sagittal (left) and axial (right)). Which of the following is the most likely diagnosis?
A 52-year-old woman is brought to the emergency room in respiratory distress. She is accompanied by her husband who stated that they were eating at a high-end sushi restaurant when his wife started to complain of perioral numbness and tingling. Two hours later she started to complain of generalized weakness and trouble breathing. Accidental poisoning is suspected. Based on the available information, what is the mechanism of action of the poison ingested?
A 57-year-old male with recently diagnosed small cell lung cancer (SCLC) is presenting to the electromyography lab with a one-month history of muscle cramps and muscle pain. Percussive myotonia is appreciated on examination. Electromyography showed myokymic discharges. Autoantibodies against which of the following channels are likely present in this case?
Which of the following medications are known to develop neutralizing antibodies (NAbs) against it with chronic use?
A 72-year-old male with a past medical history of hypertension presents with an acute onset of right upper and lower extremity weakness. The sensory exam is normal. Right homonymous hemianopia is also appreciated. Which of the following vessels is most likely affected?
Paralysis of the stapedius muscle can occur with ipsilateral damage to which cranial nerve?
Which of the following is an absolute contraindication for the use of tPA?
You are caring for a 19-year-old male in the neurocritical care unit after drowning. His brain MRI is pending clinical stability. Which finding on brain MRI is most likely after a severe global hypoxic injury?
A 32-year-old female comes into the clinic with a continuous, throbbing headache for 5 months. The pain is unilateral near the temple. The headache is constant but there are periods of pain exacerbations that can last from minutes to days and are debilitating. There is associated lacrimation and rhinorrhea on the ipsilateral side. What is the most likely diagnosis?
A 55-year-old male cigarette smoker with a past medical history of hypertension and medication non-compliance presents to the emergency room with an excruciating headache and altered mentation. An MRI of the brain is completed and provided below (T2 sequence). Which of the following is the most likely diagnosis?
Huntington’s disease is most commonly associated with which of the following?
A 9-year-old boy presents to the clinic with complaints of gait and speech trouble. His mother reports he started walking “like he was drunk” a few months ago. He had genetic testing that confirmed a trinucleotide GAA repeat expansion in one of his genes. Which of the following findings on physical exam is least likely to be present?
Which of the following arteries provides the prominent supply to the posterior limb of the internal capsule?
An 8-year-old male is seen in the clinic for difficulty paying attention at school and at home for the past 9 months. His mother reports that his elementary school teacher has called the home multiple times because the patient will often run around the classroom during assignments and frequently interrupts classmates. The mother states that at home, the patient has difficulty sitting still long enough to finish his dinner and homework. This patient’s condition is best treated with a medication that has what action?