Quiz 06/10/2022

A 20-year-old male presents to your clinic for weakness. He is the star baseball player at the local university, but during the season his batting average has been dropping, and he finds he is having trouble standing on his toes, performing overhead shoulder presses, and more recently ascending steps. You give him a script for some blood testing and an EMG/NCS and schedule a follow-up in 2 weeks.

Unfortunately, shortly after returning home he had a fall down a flight of stairs and sustained a compound radius fracture. He was taken to the emergency room where an open reduction and fixation (ORIF) was performed. Shortly after the surgery, he developed tachycardia, tachypnea, and masseter muscle contractions, which then progressed to fever and rigidity.

Which of the following test results is most likely to be seen in this patient?

Which of the following anti-seizure medications carries the highest risk of major congenital malformations?

Anti-Ma2 autoantibodies are most commonly associated with which of the following tumors?

How long ago did the ischemic injury seen on this neuronal tissue micropathology slide occur?

What is the mechanism of action of clopidogrel?

Which of the following structures is not primarily involved in the processing and relay of auditory information in the central nervous system?

Which of the following anatomic structures is responsible for the perception of superficial light touch?

Which of the following is the most likely diagnosis based on the EMG provided below?

A 67-year-old man presents urgently to the emergency room with an acute onset of left-sided weakness and numbness. A CT head was performed and shown below. What is the most likely etiology of the patient’s symptoms?

A 15-day-old female is evaluated in the NICU after being born to a G2P2 mother. On exam, the infant is jaundiced. Abdominal ultrasound shows severe hepatosplenomegaly. CT scan of the head shows hydrocephalus and periventricular calcifications, and a fundoscopic exam shows bilateral chorioretinitis. Serological testing is most likely to show infection with which organism?

Which of the following is the mechanism of action of ocrelizumab?

A 66-year-old right-handed male presents to the EMG/NCS lab with right upper extremity pain, numbness, and weakness. Based on the data collected, what is the most likely diagnosis?

A 43-year-old man with obesity and hypertension presents with complaints of excessive daytime sleepiness, gasping awakenings, and witnessed periods of not breathing during sleep. A polysomnogram is performed and confirms the presence of sleep-disordered breathing. What feature would point to a central rather than obstructive cause?

A lesion to which of the following hypothalamic nuclei can lead to hyperthermia?

A 60-year-old woman with a history of diabetes is presenting to the neurology clinic with a 4-month history of burning/tingling in her bilateral toes. Neurological examination revealed 5/5 strength in all muscle groups, normal reflexes, and intact sensation to light touch in the bilateral lower extremities. There was mildly decreased sensation to pinprick in the 1^st toe bilaterally. Which of the following tests is the most likely to be diagnostic for this patient?