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A morbidly obese patient with a past medical history of brainstem stroke and excessive daytime sleepiness undergoes polysomnography. Polysomnographic testing revealed an average of 8-10 apnea/hypopneas per hour during sleep. During prolonged periods of apnea, there were no out-of-phase movements on plethysmography. Which of the following is the most likely diagnosis?
Which of the following medications used in the management of multiple sclerosis is the most teratogenic?
Which of the following medications has the highest risk for QT prolongation?
A 65-year-old mechanical engineer presents with increasing word-finding difficulties. He is particularly concerned that he is forgetting the names of people, places, and objects. On examination, he has difficulty naming objects when shown (i.e. keys, watch, etc.). Otherwise, his speech is fluent. A SPECT scan shows hypometabolism in the left anterior temporal lobe. Which of the following is the most likely diagnosis?
A 62-year-old man complains of 5 years of vivid dreams. At times this involves punching and kicking, which has hurt his wife. He undergoes a polysomnogram and there is no sleep-disordered breathing and the EEG is normal. What would be the best first-line medication to treat this behavior?
A 65-year-old woman with a past medical history of hypertension presents with recent onset of bilateral eye discomfort and diplopia. She states that she is unable to completely close her eyes. On exam, pain is elicited when testing extraocular movements. Visual acuity and visual fields are unremarkable. MRI of the brain reveals excessive peri-orbital subcutaneous tissue bilaterally. Which of the following is the most likely diagnosis?
Which of the following is not a recommended screening test for cognitive dysfunction?
Exposure to which of the following in utero is associated with low birth weight?
Which of the following infectious agents is most likely responsible for the pathology seen in the image below?
A 65-year-old female presents to the Emergency Room with a 2-month history of altered mental status and jerking. On examination, you appreciate an exaggerated startle response. Her MRI was shown below. Which of the following statements is true?
A 72 y.o. female presents to the clinic with complaints of decreased interest in eating, and has lost weight. She states foods have an unusual taste and are not appealing. On detailed examination, she is found to have normal extraocular movements, normal facial muscle symmetry, and normal facial sensation and swallowing. On further detailed examination, she has a loss of taste sensation in the right anterior two-thirds of her tongue. Of the following, which is the most likely area of injury?
Patients with Krabbe disease have a pathologic accumulation of which of the following?
A 27-year-old presents to the clinic with finger extension, wrist extension, shoulder abduction, and shoulder adduction weakness. There is also numbness along the lateral and posterior arm. Which of the following is the most likely cause of the patient’s symptoms?
Which of the following can increase the risk of seizures while taking bupropion?
Which of the anti-seizure medications (ASMs) listed operates under zero-order kinetics at high doses?