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A pediatric neurology consult was placed for a 5-day-old, full-term newborn with macrocephaly. When formally measured his head circumference was 46 cm. A tense fontanelle was appreciated on examination. A bedside ultrasound was performed and the only abnormality appreciated was significant hydrocephalus. What is the most likely etiology of the patient’s symptoms?
A 3-year-old male with a history of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) was referred to neurology by his PCP for concern of a genetic disorder. On examination, the patient appears to have a long face, large ears, and a prominent jaw. Genetic testing shows that the patient has a pathologic gene mutation with over 200 trinucleotide CGG repeats. Which of the following is a comorbidity appreciated in this patient’s neurologic syndrome?
Which of the following findings is depicted in the MR Angiogram shown below?
Which of the following is the mechanism of action for amantadine?
A 6-month-old full-term female is referred to the clinic with persistent right shoulder and elbow weakness since birth. Which of the following is the most likely pathologic lesion?
A 62-year-old man complains of 5 years of vivid dreams. At times this involves punching and kicking, which has hurt his wife. He undergoes a polysomnogram and there is no sleep-disordered breathing and the EEG is normal. What would be the best first-line medication to treat this behavior?
Which of the following is true regarding IVIG and PLEX therapy?
A 32-year-old man with a past medical history significant for major depressive disorder is brought to the emergency department after he was found by his roommate attempting suicide by hanging. His roommate states that he has been noncompliant with his medications and had been going through a depressive episode before his suicide attempt. After 6 weeks of trying several different antidepressants while on the inpatient psychiatric service, his major depression symptoms have not improved. Which of the following is the most appropriate next step in treatment?
Which of the following is the antibody associated with dermatomyositis that is known to confer the highest risk of cancer?
A patient with relapsing-remitting multiple sclerosis presents to the emergency department with a new headache, confusion, and vision loss. A T2 sequence from their MRI is shown below. Lumbar puncture is positive for JCV in the CSF. What is the mechanism of action of the disease-modifying therapy most likely to be attributed to this clinical scenario?
Which of the following antiplatelet medications rely heavily on the cytochrome P450 system for its therapeutic effect?
Which of the following is present in the image shown below?
This muscle biopsy is most consistent with which myopathic disease?
The pathology slide below is most consistent with which of the following disorders?