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A 12-year-old patient with neurofibromatosis type I is found to have a cerebellar cystic mass with a mural nodule and contrast-enhancing rim after presenting with symptoms of increased intracranial pressure. The lesion was surgically resected and an example of the pathologic findings is shown below. What is the most likely diagnosis?
This brain biopsy is representative of which of the following tumors?
An 8-year-old girl is brought to the clinic by her mother for complaints of progressive insomnia, difficulty walking, and worsening vision. On exam, the patient is found to be unable to look upwards and her pupils accommodate but fail to react to light. On further questioning, it is found that menarche occurred at 7 years of age. MRI is most likely to demonstrate a tumor of which brain structure?
A 35-year-old woman presents to the clinic with headaches. Her past medical history is significant for migraines and a sprained ankle four months ago that she has been managing with daily NSAIDs. Her headaches started a month ago and have been occurring every day for the past three weeks. She describes the headaches as a band-like pressure around her head. Nothing has helped but the symptoms are worse in the mornings. A recent brain MRI was completed during an emergency room visit which was unremarkable. Which of the following is the most appropriate next step in therapy?
A 6-month-old previously healthy male is seen in your clinic due to feeding difficulties and weakness for the past 8 days. The mother reports that he has also not had a bowel movement in 3 days. On physical exam, the patient demonstrates a weak cry, severe hypotonia, and hypo-responsiveness. No one else in the family is sick, however, they have been eating homemade molasses for the past 4 weeks. This patient’s condition is caused by a toxin affecting which structure?
Which of the following antiplatelet medications rely heavily on the cytochrome P450 system for its therapeutic effect?
A 30-year-old female with a past medical history significant for acne, migraine without aura, and depression presents to the emergency room with severe recurrent headaches. She says the headaches come on quickly and only last a couple of minutes but are debilitating. CTH was normal. A CTA head and neck was performed which showed segmental artery narrowing in the proximal MCA territory. Which of the following medications was the most likely trigger of this patient’s presentation?
What are the 3 most common causes of bacterial meningitis in neonates (0-1 months)?
The pathology seen in the image below is most likely related to maternal use of which of the following medications?
A 33-year-old woman with a past medical history of depression is brought to the clinic by her husband because of atypical behavior. For the past three weeks, her thoughts have become progressively more disorganized. She is also having auditory hallucinations. Similar behavior has been seen intermittently over the past five years. Despite having a history of depression, her husband says the depression has been well controlled for the last three months. Which of the following is the most likely diagnosis?
Pilocytic astrocytomas characteristically have which of the following genetic abnormalities?
Based on the histopathologic findings shown below, how long ago did this patient experience an ischemic stroke?
A 3-day-old male infant is evaluated in the NICU for fever and focal seizures. He was born at 39 weeks gestation via uncomplicated vaginal delivery and had good APGAR scores. Brain imaging shows periventricular calcifications and severe ventriculomegaly. Auditory testing also demonstrates bilateral hearing impairment. What is the most likely cause of the patient’s symptoms?
Of the following, which region of the adult brain is most susceptible to hypoperfusion injury and ischemia?
This pathology slide is most consistent with which of the following diseases?