Quiz 07/16/2022 (2)

Which of the following is not a known side effect of chronic phenytoin use?

A 72-year-old female presents to the clinic with her husband who states that she is “seeing things that aren’t there”. For the past two weeks, she has been complaining of bats flying around her room at night. Comparable visual disturbances have occurred over the past year, but have gotten progressively worse recently. She has also been acting out a lot at night; her husband states that she has been violently kicking and flailing her arms while asleep. Finally, she has been experiencing cognitive decline, including forgetting where she lives, what year it is, and the names of her grandchildren. On exam, there is symmetric cog-wheel rigidity appreciated. What is the most likely diagnosis?

A 34-year-old man was admitted to the hospital and intubated after a severe motor vehicle accident leading to multiple bone fractures two days ago. Despite weaning IV sedation, the patient continues to be unarousable to stimulation. An MRI was performed and DWI imaging is shown below. What is the most likely diagnosis?

A 34-year-old female with poorly-controlled type 2 diabetes presents to the ED with a 3-day history of sinus and orbital pain, fever, and headache. Four hours ago, she was feeling confused and dizzy, which prompted her to come to the hospital. A head CT scan is performed and it shows erosion of the nasal bones and obliteration of the sinuses. Biopsy of antral tissue shows fungal hyphae. What is the most likely diagnosis?

Pilocytic astrocytomas characteristically have which of the following genetic abnormalities?