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A mutation in which of the following genes would be most likely in a patient with numerous cavernous malformations seen on head imaging?
Which of the following statements regarding Alexander’s disease is incorrect?
Which of the following testing can be used to diagnose a small fiber neuropathy?
Which of the following is the primary source of norepinephrine in the brain?
A 42-year-old man with a longstanding history of chronic alcohol abuse was found down unresponsive in a public park. He was intubated in the field and brought emergently to the emergency room where his blood alcohol level was 0.32%. A chest X-ray revealed aspiration pneumonia. He was admitted to the ICU, sedated, started on broad-spectrum antibiotics, and aggressively fluid resuscitated. On the second day of the hospitalization, the sedative was weaned but the patient remained comatose. An MRI was performed to identify a possible cause of his symptoms. What is the most likely diagnosis?
A 40-year-old previously healthy man arrives in the emergency room with a 1-week history of slowly progressive leg weakness. Symptoms initially started with burning-type pain in his bilateral lower extremities. Neurological examination shows 4-/5 strength in bilateral lower extremities and areflexia of the patella and Achilles. MRI is shown below. Which of the following is the most likely diagnosis?
A lesion to which of the following hypothalamic nuclei causes hyperphagia?
Patients with Von-Hippel Lindau (VHL) syndrome are at risk of developing which of the following?
Which of the following is the reversal agent for dabigatran?
A 45-year-old patient presented to the emergency room unresponsive. Emergency medical services noted that the patient was found in his garage with the car running in an apparent suicide attempt. Despite appropriate medical care, the patient passed away. An autopsy was performed. A gross pathology image is shown below. Identify the following regions marked by the white arrows.
A 4-year-old girl with multiple seizure types and intellectual disability has an EEG performed that shows 1.5 Hz to 2.5 Hz spike and wave discharges. Which of the following is the most likely diagnosis?
A 38-year-old man presents with frequent headaches over the past year and recent development of polydipsia and polyuria. He has also been complaining of a dry cough, shortness of breath, and erythematous nodules along his shins bilaterally. MRI of the brain shows a contrast-enhancing lesion of the hypothalamus. Which of the following is the most likely diagnosis?
This muscle biopsy is most consistent with which myopathic disease?
A 72-year-old male with a past medical history of hypertension presents with an acute onset of right upper and lower extremity weakness. The sensory exam is normal. Right homonymous hemianopia is also appreciated. Which of the following vessels is most likely affected?
Which of the following drug-mechanism pairs is incorrect?