Quiz 07/31/2022 (6)

Which of the following genetic disorders is most commonly associated with holoprosencephaly?

A 5-month-old female is brought to the emergency room by her parents because of an episode concerning for possible seizure. On arrival, the patient appears back to her clinical baseline neurologically. Several hypomelanotic lesions are appreciated while performing a skin check. The mother notes that her older brother has similar skin findings. An EEG is performed and shown below. A typical event was captured that correlated with an electrodecrement of cortical activity on EEG.

Based on the child’s diagnosis, what is the most appropriate therapy?

A 55-year-old male presents with progressive worsening new headache over several months. He did not wish to seek medical attention but now presents because his family reports his facial expressions “look different”. On exam, he has impaired upgaze, light near dissociation, and convergence retraction nystagmus. An MRI is done and shows a lesion. Where is the lesion likely located?

A 42-year-old man with a 6-month history of progressive muscle weakness has a nerve biopsy performed. Based on the toluidine blue (left) and trichrome (right) stain slides shown, which of the following is the most likely diagnosis?

Which of the following identifies the straight sinus?

Which of the following is most commonly associated with NMDA-receptor encephalitis?

Vasogenic edema would be best appreciated on which of the following MRI sequences?

A mother and father bring in their 8-month-old son to your clinic for clinical events described as sudden flexion of the limbs and trunk, seen most often upon awakening or falling asleep. His interictal EEG is demonstrated below. Which of the following is the most likely cause of the patient’s symptoms and EEG findings?