Queston #27406Note

Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) presents in the first two decades of life with sleep-related hyperkinetic aware seizures. Patients can have a prodrome of fear before the motor component of the seizure. Mutations of nicotinic acetylcholine receptor genes CNRNA4 or CHRNB2 can cause this epilepsy syndrome