Symmetric T2 hyperintense lesions in the basal ganglia, periaquedutal grey, and cerebral peduncles or brainstem can be seen in Leigh Symdome
Leigh Syndrome
– a progressive neurodegenerative mitochondrial disorder that typically presents in the first year of life
– Signx + sx: psychomotor regression, vomiting, diarrhea, dysphagia, failure to thrive, dystonia, ataxia, and ophthalmoparesis